Line an 8" square dish with parchment paper then set aside.
Add white chocolate chips, sweetened condensed milk and butter to a microwave safe mixing bowl. Heat in 30-second intervals, stirring between each time until chocolate chips and butter are about 90% melted.
Remove from microwave. Scrape the insides of the vanilla bean into the bowl then continue to stir until chocolate chips are completely melted and all ingredients have blended evenly. Add Irish cream and powdered sugar then stir until smooth.
Pour fudge into prepared pan then refrigerate for about 2 hours or until firmly set. Remove from refrigerator then invert pan onto a cutting board. Discard parchment paper, cut fudge into squares then serve.
Notes
This recipe contains a hint of Irish cream flavor without the overpowering taste of alcohol!